In the first major departures for "Parks and Recreation," two of the show’s stars are headed out. The New York Times’ ArtsBeat reports that Rashida Jones and Rob Lowe are departing the NBC comedy.

Lowe, who plays the enthusiastic Chris Traeger, and Jones, who plays the nurse Ann Perkins, will leave following the 13th episode of the upcoming sixth season, the story says. The characters dated for a while, and in the latest season, were planning to have a child together while keeping their relationship platonic.

"We’ve been working on their storyline (on and off) for four seasons now, and heading into this year, with the two of them contemplating parenthood, it felt like a natural time to move them into the next phase," said producer Michael Schur in a statement.

He added, "We absolutely love both Rashida and Rob, and will be sad to see them go. Rashida was one of the very first people we knew we wanted in the cast, and as important as Ann is to Leslie (and vice-versa), she’ll certainly never be far from Pawnee. Rob we initially thought we could only have for six or eight episodes, and we couldn’t be happier that he will have stuck around for 75."