Jamie Lee Curtis has been signed for a drama pilot on CBS, reports our friend Nellie Andreeva at Deadline.com.

The pilot is an untitled project from David Marshall Grant.

The story reports: "The soapy medical show, based on an Israeli format, revolves around quadruplets — three brothers and a sister — who grew up on a reality show. Curtis will play their mother, Caroline, a dynamic and distinguished physician who now runs the hospital. This marks Curtis’ first series regular role since 1989′s ‘Anything But Love.’"

Curtis has also appeared on CBS’s "NCIS."

Jamie Lee Curtis