Meredith Vieira will revisit a colorful role from her past with an appearance on a soap opera later this week, ABC announced.

The host of “Who Wants to Be a Millionaire” will check in to ABC’s “General Hospital” to reprise her role as Bree Flanders, who was a high-class madam last time around. Vieira, a multiple Emmy Award winner, previously played the role in March 2003.

Vieira will appear on the daytime drama on Friday, Dec. 14 (2 p.m. ET, 1 p.m. PT/CT).

Said Vieira: “I actually resurrected a character, Bree Flanders, that I played ten years ago. At that point she was a madam. Now she’s a senior vice president of a company, so she’s definitely improved her lot in life. It strikes me every time I do anything with a soap opera — but just working with ‘General Hospital’ — so impressed with the actors, they’re so good. They have to learn so much material on a day-to-day basis. You know, ten years ago I had a better memory than now, so I was a little intimidated, but it worked out great.”

ABC noted: “Vieira’s appearance also helps to usher in the return of fan favorite Lucy Coe, played by Lynn Herring, who also marks her return to ‘General Hospital’ on Friday, Dec. 14.”

The long-running soap will mark its 50th anniversary on April 1-2, 2013.