NBC is overhauling a high-profile comedy project, and has let go three cast members–almost half the cast–reports TVLine.com. 

The show is the upcoming "Are You There, Vodka? It’s Me, Chelsea," based on Chelsea Handler’s best-selling comic memoir. The show has let go "White Collar" alum Natalie Morales, former "ER" actress Angel Laketa Moore and comedian Jo Koy, the story says.

A representative for the show said those three cast members were being let go for creative reasons, and their characters are being reconceived.

Morales was slated to play Handler’s best friend, while Moore and Koy had been cast as co-workers.

"Vodka" is scheduled for midseason.