HBO has canceled a series after a three-season run on the premium cable channel. Variety reports that the channel pulled the plug on the adult-focused animated series “Animals.”

“The series was created by executive producers Phil Matarese and Mike Luciano, with Duplass Brothers Productions producing,” Variety notes. “The animated comedy series focused on the downtrodden creatures native [to] New York City,  including rats, pigeons, and bedbugs. Matarese and Luciano also wrote and directed all the episodes, and voiced many of the characters.”

The series featured a string of high-profile guest actors in voice roles, with Awkwafina, Marcia Clark, Edie Falco, Lucy Liu, Carol Kane, Johnny Knoxville, John Leguizamo, Natasha Lyonne, Tatiana Maslany, Demi Moore and Moby among those appearing in season three alone.

“Mark Duplass and Jay Duplass also executive produce the series, with producers James Fino, Joe Russo II, Kenny Micka, and co-executive producer Jen Roskind,” Variety notes.